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Macrophage / Histiocytoma Marker Antikörper

Reaktivität: Human IHC, StM Wirt: Maus Monoclonal D11 unconjugated
Produktnummer ABIN6941389
  • Target Alle Macrophage / Histiocytoma Marker Produkte
    Macrophage / Histiocytoma Marker
    Reaktivität
    Human
    Wirt
    • 2
    Maus
    Klonalität
    • 2
    Monoklonal
    Konjugat
    • 2
    Dieser Macrophage / Histiocytoma Marker Antikörper ist unkonjugiert
    Applikation
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    In Western blotting, it detects an antigen of 125 kDa in human liver and 135 kDa in tumors of histiocytic origin. Comparative study of this MAb and a standard CD68 MAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This MAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This MAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
    Keine Kreuzreaktivität
    Maus, Schwein, Ratte (Rattus)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Membrane preparation from human hepatocytes
    Klon
    D11
    Isotyp
    IgG1 kappa
  • Applikationshinweise

    Positive Control: Liver or Histiocytoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Macrophage / Histiocytoma Marker
    Andere Bezeichnung
    Macrophage & Histiocytoma Marker (Macrophage / Histiocytoma Marker Produkte)
    Molekulargewicht
    125kDa -135kDa
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