EBV EA Antikörper
Kurzübersicht für EBV EA Antikörper (ABIN6941310)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Purified by Protein A/G
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Immunogen
- Affinity Purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt's lymphoma sera
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Isotyp
- IgG1 kappa
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Applikationshinweise
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Positive Control: EBV-infected cells. Tissues.
Known Application: Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- EBV EA (Epstein-Barr Virus Early Antigen (EBV EA))
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Andere Bezeichnung
- EBV Early Antigens (Epstein Barr Virus)
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Substanzklasse
- Viral Protein
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Hintergrund
- Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.
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Molekulargewicht
- 50/55kDa doublet
Target
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