CD7 Antikörper

Produktnummer ABIN6941065

Dieses Anti-CD7-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD7 in FACS und IF. Geeignet für Human.

Kurzübersicht für CD7 Antikörper (ABIN6941065)

Target: CD7

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: B-F12

Produktdetails anti-CD7 Antikörper

Spezifität: Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

Aufreinigung: Purified by Protein A/G

Immunogen: Chronic Lymphoid Leukemia cells (CLL)

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Jurkat, HUT-78, Molt-4, CEM cells or human peripheral blood lymphocytes. Lymph node and tonsil.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD7

Target: CD7

Andere Bezeichnung: CD7

Molekulargewicht: 40kDa

Gen-ID: 924

UniProt: P09564

Pathways: Cell-Cell Junction Organization