CD4 Antikörper

Produktnummer ABIN6941040

Der Maus Monoklonal anti-CD4 Antikörper (Klon RIV7) (ABIN6941040) detektiert spezifisch CD4 in FACS, IF und Func. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Affe.

Kurzübersicht für CD4 Antikörper (ABIN6941040)

Target: CD4

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Klon: RIV7

Produktdetails anti-CD4 Antikörper

Spezifität: Recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Aufreinigung: Purified by Protein A/G

Immunogen: Human peripheral lymphocytes

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Human peripheral blood mononuclear cells (PBMCs), CCRF-CEM or HL-60. Lymph node or tonsil.

Known Application: Functional Studies (Order Ab without azide), Flow Cytometry (1-2 μg/million cells in 0.1ml), Immunofluorescence (1-2 μg/mL) Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Molekulargewicht: 55kDa

Gen-ID: 920

UniProt: P01730

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events