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CD4 Antikörper

CD4 Reaktivität: Human, Orang-Utan, Macaca arctoides, Schimpanse FACS, IF, Func Wirt: Maus Monoclonal EDU-2 unconjugated
Produktnummer ABIN6941039
  • Target Alle CD4 Antikörper anzeigen
    CD4
    Reaktivität
    • 363
    • 230
    • 126
    • 48
    • 24
    • 22
    • 20
    • 19
    • 17
    • 10
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Orang-Utan, Macaca arctoides, Schimpanse
    Wirt
    • 386
    • 147
    • 135
    • 3
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 530
    • 138
    • 5
    Monoklonal
    Konjugat
    • 213
    • 72
    • 63
    • 47
    • 35
    • 16
    • 12
    • 11
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser CD4 Antikörper ist unkonjugiert
    Applikation
    • 537
    • 202
    • 138
    • 116
    • 99
    • 73
    • 69
    • 42
    • 39
    • 31
    • 31
    • 30
    • 17
    • 10
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    Spezifität
    Recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.This MAb was characterized as human CD4 antibody at II and IV International Workshop on Human Leukocyte Differentiation Antigens.
    Keine Kreuzreaktivität
    Rhesusaffen
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Stimulated human leukocytes
    Klon
    EDU-2
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD4 Primärantikörper
  • Applikationshinweise

    Positive Control: Human peripheral blood mononuclear cells (PBMCs), CCRF-CEM or HL-60. Lymph node or tonsil.

    Known Application: Functional Studies (Order Ab without azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    CD4
    Andere Bezeichnung
    CD4 (CD4 Produkte)
    Molekulargewicht
    55kDa
    Gen-ID
    920
    UniProt
    P01730
    Pathways
    T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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