Uroplakin 3A Antikörper (AA 260-279)
Kurzübersicht für Uroplakin 3A Antikörper (AA 260-279) (ABIN6940860)
Target
Alle Uroplakin 3A (UPK3A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 260-279
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Immunogen
- A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A
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Isotyp
- IgG
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Applikationshinweise
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Positive Control: HEK293 cells. Bladder carcinoma.
Known Application: Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- Uroplakin 3A (UPK3A)
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Andere Bezeichnung
- UPK3A
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Hintergrund
- Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
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Gen-ID
- 7380
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UniProt
- O75631
Target
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