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TFF1 Antikörper

This anti-TFF1 antibody (ABIN6940690) is a Mouse Monoclonal antibody detecting TFF1 in IHC, IF, FACS, StM. Suitable for Human.
Produktnummer ABIN6940690

Kurzübersicht für TFF1 Antikörper (ABIN6940690)

Target

Alle TFF1 Antikörper anzeigen
TFF1 (Trefoil Factor 1 (TFF1))

Reaktivität

  • 86
  • 18
  • 16
  • 13
  • 11
Human

Wirt

  • 54
  • 45
Maus

Klonalität

  • 50
  • 49
Monoklonal

Konjugat

  • 65
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser TFF1 Antikörper ist unkonjugiert

Applikation

  • 58
  • 46
  • 35
  • 29
  • 19
  • 18
  • 14
  • 9
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)

Klon

TFF1-2133
  • Spezifität

    It recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant full-length human TFF1 protein

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Positive Control: MCF-7 cells, Breast or Ovarian carcinoma.

    Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    TFF1 (Trefoil Factor 1 (TFF1))

    Andere Bezeichnung

    TFF1

    Molekulargewicht

    6.5kDa

    Gen-ID

    7031

    UniProt

    P04155

    Pathways

    EGFR Signaling Pathway
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