CD147 Antikörper

Produktnummer ABIN6940674

Produktdetails anti-CD147 Antikörper

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD147 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Aggregation (AGG), Staining Methods (StM)

Spezifität: This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Aufreinigung: Purified by Protein A/G

Immunogen: Human T cell line Molt 13

Klon: 8D6

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma.

Known Application: Inhibits Homotypic Aggregation, Adhesion to Matrix Proteins, and Migation through Matrigel (Order Ab without BSA/Azide),Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1:100-1:200), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Andere Bezeichnung: BSG (BSG Produkte)

Synonyme: EMMPRIN antikoerper, RPE7 antikoerper, 5F7 antikoerper, CD147 antikoerper, M6 antikoerper, OK antikoerper, TCSF antikoerper, AI115436 antikoerper, AI325119 antikoerper, HT-7 antikoerper, 5A11 antikoerper, CE9 antikoerper, HT7 antikoerper, Ox47R antikoerper, basignin antikoerper, wu:fb26a05 antikoerper, wu:fo98e12 antikoerper, bsg antikoerper, prso03 antikoerper, basigin (Ok blood group) antikoerper, basigin antikoerper, basigin (Ok blood group) S homeolog antikoerper, BSG antikoerper, Bsg antikoerper, bsg antikoerper, bsg.S antikoerper

Molekulargewicht: 35kDa (non-reduced), 40kDa (reduced)

Gen-ID: 682

UniProt: P35613

Pathways: S100 Proteine