RBP4 Antikörper

Produktnummer ABIN6940482

Produktdetails anti-RBP4 Antikörper

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Reaktivität: Human, Maus, Ratte, Kaninchen, Affe, Ziege, Schimpanse

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RBP4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Spezifität: This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.

Aufreinigung: Purified by Protein A/G

Immunogen: Retinol binding protein-1 Purified from human plasma

Klon: G4E4

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Hepatic or Ovarian Carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu RBP4

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Andere Bezeichnung: RBP (RBP4 Produkte)

Synonyme: RDCCAS antikoerper, RBP antikoerper, RNBP antikoerper, rbp4 antikoerper, MGC54038 antikoerper, srbp antikoerper, PRBP antikoerper, RBPA antikoerper, Rbp-4 antikoerper, fb23c12 antikoerper, rbp antikoerper, wu:fb23c12 antikoerper, wu:fb58d04 antikoerper, wu:fb72b04 antikoerper, zgc:86911 antikoerper, retinol binding protein 4 antikoerper, renin binding protein antikoerper, retinol binding protein 4 S homeolog antikoerper, retinol binding protein 4 A, plasma antikoerper, retinol binding protein 4, plasma antikoerper, retinol binding protein 4 L homeolog antikoerper, RBP4 antikoerper, RENBP antikoerper, rbp4.S antikoerper, rbp4 antikoerper, Rbp4 antikoerper, RBP4A antikoerper, rbp4.L antikoerper

Molekulargewicht: 21-25kDa

Gen-ID: 5947, 5948, 5950

UniProt: P02753, P09455, P50120

Pathways: Regulatorische RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response