Rekombinanter CD207 Antikörper (AA 74-213)

Produktnummer ABIN6940245

Dieses Anti-CD207-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD207 in WB, ELISA und Coat. Geeignet für Human.

Kurzübersicht für Rekombinanter CD207 Antikörper (AA 74-213) (ABIN6940245)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Coating (Coat)

Klon: RLGRN-1821

Produktdetails anti-CD207 Antikörper

Bindungsspezifität: AA 74-213

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: HeLa or A549 cells (WB).

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: CD207

Hintergrund: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

Molekulargewicht: 48kDa

Gen-ID: 50489

UniProt: Q9UJ71