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Nkx2-2 Antikörper

Nkx2-2 Reaktivität: Human IHC, StM Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6940207
  • Target Alle Nkx2-2 Antikörper anzeigen
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    Reaktivität
    • 106
    • 51
    • 44
    • 23
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 67
    • 49
    Kaninchen
    Klonalität
    • 64
    • 52
    Polyklonal
    Konjugat
    • 54
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Nkx2-2 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 47
    • 38
    • 38
    • 30
    • 14
    • 13
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
    Immunogen
    Recombinant human NKX2.2 protein fragment
    Isotyp
    IgG
    Top Product
    Discover our top product Nkx2-2 Primärantikörper
  • Applikationshinweise

    Positive Control: Pancreas or Ewing's sarcoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
    Andere Bezeichnung
    NKX2-2 (Nkx2-2 Produkte)
    Synonyme
    XeNK-2 antikoerper, Xnkx2.2 antikoerper, nkx2-2-A antikoerper, nkx2.2 antikoerper, NKX-2.2 antikoerper, NKX2.2 antikoerper, NKX2B antikoerper, Nkx-2.2 antikoerper, Nkx2.2 antikoerper, tinman antikoerper, id:ibd5090 antikoerper, nk2.2 antikoerper, nkx2-2 antikoerper, wu:fc83b01 antikoerper, zgc:136536 antikoerper, NK2 homeobox 2 S homeolog antikoerper, NK2 homeobox 2 antikoerper, NK2 homeobox 2a antikoerper, nkx2-2.S antikoerper, NKX2-2 antikoerper, Nkx2-2 antikoerper, nkx2.2a antikoerper
    Molekulargewicht
    40-50kDa
    Gen-ID
    4821
    UniProt
    O95096
    Pathways
    Dopaminergic Neurogenesis
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