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MUC4 Antikörper (AA 1730-1864)

Dieses Anti-MUC4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MUC4 in IHC und StM. Geeignet für Human.
Produktnummer ABIN6940126

Kurzübersicht für MUC4 Antikörper (AA 1730-1864) (ABIN6940126)

Target

Alle MUC4 Antikörper anzeigen
MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Reaktivität

  • 67
  • 15
  • 6
  • 1
Human

Wirt

  • 37
  • 35
Maus

Klonalität

  • 44
  • 28
Monoklonal

Konjugat

  • 45
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MUC4 Antikörper ist unkonjugiert

Applikation

  • 44
  • 37
  • 20
  • 16
  • 12
  • 10
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

Klon

MUC4-3105
  • Bindungsspezifität

    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1730-1864

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant fragment (around aa 1730-1864) of human MUC4 protein (exact sequence is proprietary)

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Positive Control: Stomach, Colon or esophagus.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    MUC4 (Mucin 4, Cell Surface Associated (MUC4))

    Andere Bezeichnung

    MUC4

    Hintergrund

    The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a very specific (100 % ) and sensitive (90 %) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.

    Molekulargewicht

    235kDa

    Gen-ID

    4585

    UniProt

    Q99102

    Pathways

    Regulation of Leukocyte Mediated Immunity
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