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Rekombinanter Moesin Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Moesin in WB, IHC, IF, FACS und StM. Er zeigt eine Reaktivität gegenüber Human und Ratte.
Produktnummer ABIN6940086

Kurzübersicht für Rekombinanter Moesin Antikörper (ABIN6940086)

Target

Alle Moesin (MSN) Antikörper anzeigen
Moesin (MSN)

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 105
  • 64
  • 29
  • 8
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Human, Ratte

Wirt

  • 68
  • 46
  • 1
Maus

Klonalität

  • 59
  • 55
Monoklonal

Konjugat

  • 65
  • 8
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser Moesin Antikörper ist unkonjugiert

Applikation

  • 97
  • 56
  • 49
  • 34
  • 28
  • 22
  • 17
  • 16
  • 11
  • 10
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)

Klon

RMSN-492
  • Spezifität

    Recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant full-length human Moesin protein

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Positive Control: HT-29, Jurkat, CH3LC or HUVEC cells. Uterus, Placenta, Tonsil, Melanoma, Testicular Carcinoma.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (2-4 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    Moesin (MSN)

    Andere Bezeichnung

    MSN

    Molekulargewicht

    78kDa

    Gen-ID

    4478

    UniProt

    P26038

    Pathways

    Asymmetric Protein Localization
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