Rekombinanter Myoglobin Antikörper

Produktnummer ABIN6940005

Der Maus Monoklonal Anti-Myoglobin-Antikörper wurde für IHC und StM validiert. Er ist geeignet, Myoglobin in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Rekombinanter Myoglobin Antikörper (ABIN6940005)

Target: Myoglobin (MB)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Myoglobin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Klon: RMB-2105

Produktdetails anti-Myoglobin Antikörper

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human full-length Myoglobin (MB) protein.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: SK-BR3 or T47D cells. Skeletal or Cardiac Muscle.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Myoglobin

Target: Myoglobin (MB)

Andere Bezeichnung: Myoglobin (Muscle Cell Marker)

Hintergrund: Myoglobin is a cytosolic oxygen-binding protein responsible for the storage and diffusion of oxygen within myocytes. Expression of myoglobin is highest in skeletal and cardiac muscle. Myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia.In combination with other striated muscle markers such as vimentin and myogenin, myoglobin is helpful in the identification of rhabdomyosarcoma and tumors with skeletal muscle differentiation. Reportedly, myoglobin is expressed on epithelial cancer cells due to changed metabolic and environmental conditions.

Molekulargewicht: 17kDa

Gen-ID: 4151

UniProt: P02144

Pathways: Brown Fat Cell Differentiation