Myoglobin Antikörper

Produktnummer ABIN6940004

Dieser Maus Monoklonal Antikörper detektiert spezifisch Myoglobin in IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus und Hund.

Kurzübersicht für Myoglobin Antikörper (ABIN6940004)

Target: Myoglobin (MB)

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Myoglobin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MB-2105

Produktdetails anti-Myoglobin Antikörper

Verwendungszweck: Myoglobin (Muscle Cell Marker) Antibody

Spezifität: Myoglobin is a cytosolic oxygen-binding protein responsible for the storage and diffusion of oxygen within myocytes. Expression of myoglobin is highest in skeletal and cardiac muscle. Myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia.In combination with other striated muscle markers such as vimentin and myogenin, myoglobin is helpful in the identification of rhabdomyosarcoma and tumors with skeletal muscle differentiation. Reportedly, myoglobin is expressed on epithelial cancer cells due to changed metabolic and environmental conditions.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human full-length Myoglobin (MB) protein.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: SK-BR3 or T47D cells. Skeletal or Cardiac Muscle.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Myoglobin

Target: Myoglobin (MB)

Andere Bezeichnung: Myoglobin (Muscle Cell Marker)

Hintergrund:

MB, Myoglobin, PVALB

SK-BR3 or T47D cells. Skeletal or Cardiac Muscle.

Molekulargewicht: 17kDa

Gen-ID: 4151, 517586

UniProt: P02144

Pathways: Brown Fat Cell Differentiation