L1CAM Antikörper
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- Target Alle L1CAM Antikörper anzeigen
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser L1CAM Antikörper ist unkonjugiert
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Applikation
- ELISA, Coating (Coat)
- Spezifität
- Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Homogenous suspension of 16-week human fetal brain
- Klon
- UJ127
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product L1CAM Primärantikörper
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- Applikationshinweise
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Positive Control: Neuroblastomas or Schwannomas.
Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- Andere Bezeichnung
- L1CAM (L1CAM Produkte)
- Molekulargewicht
- 220-240kDa
- Gen-ID
- 3897
- UniProt
- P32004
- Pathways
- Synaptic Membrane
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