Rekombinanter Cytokeratin 19 Antikörper

Produktnummer ABIN6939951

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch Cytokeratin 19 in WB, IHC und StM. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Rekombinanter Cytokeratin 19 Antikörper (ABIN6939951)

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Klon: KRT19-1959R

Produktdetails anti-Cytokeratin 19 Antikörper

Spezifität: This Ab reacts with the rod domain of human cytokeratin 19 (CK19), a polypeptide of 40 kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50 % -60 % of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human full-length KRT19 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Positive Control: Hep-G2, MCF-7, HeLa cells, Breast Cancer.

Known Application: Western Blot (0.5-2 μg/mL),Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Cytokeratin 19

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Andere Bezeichnung: KRT19

Molekulargewicht: 40kDa

Gen-ID: 3880

UniProt: P08727