Rekombinanter KRT15 Antikörper

Produktnummer ABIN6939916

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch KRT15 in IHC, FACS und StM. Er zeigt eine Reaktivität gegenüber Human, Ratte und Rind (Kuh).

Kurzübersicht für Rekombinanter KRT15 Antikörper (ABIN6939916)

Target: KRT15 (Keratin 15 (KRT15))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KRT15 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)

Klon: KRT15-2103R

Produktdetails anti-KRT15 Antikörper

Immunogen: Recombinant human full-length KRT15 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Positive Control: HeLa, A431 cells. Skin or Colon.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu KRT15

Target: KRT15 (Keratin 15 (KRT15))

Andere Bezeichnung: KRT15

Hintergrund: Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. KRT15 is downregulated in activated keratinocytes. It is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

Molekulargewicht: 52kDa

Gen-ID: 3866

UniProt: P19012