Cytokeratin 13 Antikörper

Produktnummer ABIN6939905

Der Maus Monoklonal Anti-Cytokeratin 13-Antikörper wurde für IHC, IF und StM validiert. Er ist geeignet, Cytokeratin 13 in Proben von Human zu detektieren.

Kurzübersicht für Cytokeratin 13 Antikörper (ABIN6939905)

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 13 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)

Klon: KRT13-2213

Produktdetails anti-Cytokeratin 13 Antikörper

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human KRT13 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Positive Control: HeLa or A431 cells. Skin or Squamous cell carcinoma.

Known Application: Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Cytokeratin 13

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Andere Bezeichnung: KRT13

Hintergrund: Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.

Molekulargewicht: 52kDa

Gen-ID: 3860

UniProt: P13646