CD103 Antikörper

Produktnummer ABIN6939806

Der Maus Monoklonal anti-CD103 Antikörper wird verwendet zum Nachweis von CD103 in Proben von Human. Er wurde validiert für IHC und StM.

Kurzübersicht für CD103 Antikörper (ABIN6939806)

Target: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD103 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Klon: ITGAE-2063

Produktdetails anti-CD103 Antikörper

Spezifität: This MAb recognizes a protein of 150 kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95 % of intraepithelial CD8+ cells and on 40 % of mucosa-associated T cells, whereas less than 2 % of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human ITGAE protein fragment (exact sequence is proprietary)

Isotyp: IgG2c kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Tonsil, Colon or Stomach.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD103

Target: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Andere Bezeichnung: ITGAE

Molekulargewicht: 150kDa

Gen-ID: 3682

UniProt: P38570