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Rekombinanter IgL Antikörper

Reaktivität: Human IHC, StM Wirt: Kaninchen Monoclonal LLC-3778R unconjugated Recombinant Antibody
Produktnummer ABIN6939766
  • Target Alle IgL Produkte
    IgL
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    Human
    Wirt
    • 10
    • 2
    Kaninchen
    Klonalität
    • 11
    • 1
    Monoklonal
    Konjugat
    • 11
    • 1
    Dieser IgL Antikörper ist unkonjugiert
    Applikation
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human IGL protein
    Klon
    LLC-3778R
    Isotyp
    IgG
  • Applikationshinweise

    Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    IgL
    Abstract
    IgL Produkte
    Synonyme
    IGL@ antikoerper, IGLC6 antikoerper, igl antikoerper, immunoglobulin lambda locus antikoerper, IGL antikoerper, igl@ antikoerper
    Molekulargewicht
    ~22.5kDa
    Gen-ID
    3535, 3546
    UniProt
    P01701, P01842
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