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Rekombinanter IGHM Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IGHM in IHC, StM, FACS, IF, ELISA und Coat. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6939724

Kurzübersicht für Rekombinanter IGHM Antikörper (ABIN6939724)

Target

IGHM (Immunoglobulin Heavy Constant mu (IGHM))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 27
  • 1
  • 1
Human

Wirt

  • 14
  • 13
Maus

Klonalität

  • 17
  • 10
Monoklonal

Konjugat

  • 23
  • 1
  • 1
  • 1
  • 1
Dieser IGHM Antikörper ist unkonjugiert

Applikation

  • 14
  • 14
  • 11
  • 7
  • 6
  • 6
  • 6
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Coating (Coat)

Klon

RIGHM-1623
  • Spezifität

    Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant human full-length IGHM protein

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Positive Control: 293T, Raji or hPBL cells. Human tonsil or spleen (IHC).

    Known Application: ELISA (For coating, order antibody without BSA), ,Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    IGHM (Immunoglobulin Heavy Constant mu (IGHM))

    Andere Bezeichnung

    IGHM

    Molekulargewicht

    50-75kDa

    Gen-ID

    3507

    UniProt

    P01871, P20769
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