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Rekombinanter DC-SIGN/CD209 Antikörper

Der Kaninchen Monoklonal Anti-DC-SIGN/CD209-Antikörper wurde für WB, FACS, IHC, IF, ISt und StM validiert. Er ist geeignet, DC-SIGN/CD209 in Proben von Human zu detektieren.
Produktnummer ABIN6939612

Kurzübersicht für Rekombinanter DC-SIGN/CD209 Antikörper (ABIN6939612)

Target

Alle DC-SIGN/CD209 (CD209) Antikörper anzeigen
DC-SIGN/CD209 (CD209) (CD209)

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 132
  • 28
  • 21
  • 1
  • 1
Human

Wirt

  • 86
  • 59
  • 4
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 77
  • 75
Monoklonal

Konjugat

  • 69
  • 10
  • 10
  • 7
  • 7
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation

  • 76
  • 59
  • 54
  • 32
  • 26
  • 21
  • 12
  • 9
  • 7
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunostaining (ISt), Staining Methods (StM)

Klon

C209-2749R
  • Spezifität

    DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant full-length human CD209 protein

    Isotyp

    IgG
  • Applikationshinweise

    Positive Control: THP-1 or HeLa cells (IF/FACS). Human liver or spleen lysate (WB). Human small intestine (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA Buffer, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    DC-SIGN/CD209 (CD209) (CD209)

    Andere Bezeichnung

    CD209

    Molekulargewicht

    45kDa

    Gen-ID

    30835

    UniProt

    Q9NNX6
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