Annexin a1 Antikörper

Produktnummer ABIN6939607

Dieser Maus Monoklonal Antikörper detektiert spezifisch Annexin a1 in ELISA, FACS und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Annexin a1 Antikörper (ABIN6939607)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 5E4-1

Produktdetails anti-Annexin a1 Antikörper

Verwendungszweck: Annexin A1 / (Hairy Cell Leukemia Marker) Antibody

Spezifität: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Mixture of native proteins from human bone tissues

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: A431 and K562 cell lysates. Human esophagus, placenta and prostate tissues.

Known Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: ANXA1

Hintergrund:

ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35

A431 and K562 cell lysates. Human esophagus, placenta and prostate tissues.

Molekulargewicht: 35kDa

Gen-ID: 301, 494173

UniProt: P04083

Pathways: Hormone Transport