Rekombinanter Frataxin Antikörper (AA 57-210)

Produktnummer ABIN6939443

Der Maus Monoklonal anti-Frataxin Antikörper (Klon rFXN-2124) (ABIN6939443) detektiert spezifisch Frataxin in ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Frataxin Antikörper (AA 57-210) (ABIN6939443)

Target: Frataxin (FXN)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Frataxin Antikörper ist unkonjugiert

Applikation: ELISA

Klon: RFXN-2124

Produktdetails anti-Frataxin Antikörper

Bindungsspezifität: AA 57-210

Verwendungszweck: Recombinant Frataxin (Mitochondrial Marker) Antibody

Spezifität: Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Frataxin

Target: Frataxin (FXN)

Andere Bezeichnung: FXN

Hintergrund:

CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25

HePG2, HL-60 or HEK293 cells. Pancreas and Liver.

Molekulargewicht: 14kDa

Gen-ID: 2395, 20685

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size