Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Emerin Antikörper (AA 56-167)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Emerin in WB, IHC und StM. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6939304

Kurzübersicht für Emerin Antikörper (AA 56-167) (ABIN6939304)

Target

Alle Emerin (EMD) Antikörper anzeigen
Emerin (EMD)

Reaktivität

  • 82
  • 17
  • 14
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 51
  • 31
  • 2
Maus

Klonalität

  • 50
  • 34
Monoklonal

Konjugat

  • 41
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Emerin Antikörper ist unkonjugiert

Applikation

  • 70
  • 33
  • 28
  • 20
  • 16
  • 13
  • 13
  • 8
  • 8
  • 7
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Klon

EMD-2168
  • Bindungsspezifität

    • 23
    • 15
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 56-167

    Aufreinigung

    Purified by Protein A/G

    Immunogen

    Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)

    Isotyp

    IgG2b kappa
  • Applikationshinweise

    Positive Control: K-562, HeLa or Jurkat cells. Kidney or Skin.

    Known Application: Western Blot (0.5-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-80 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Haltbarkeit

    24 months
  • Target

    Emerin (EMD)

    Andere Bezeichnung

    EMD

    Hintergrund

    Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.

    Molekulargewicht

    37kDa

    Gen-ID

    2010

    UniProt

    P50402
Sie sind hier:
Chat with us!