Elastin Antikörper

Produktnummer ABIN6939301

Der Maus Monoklonal Anti-Elastin-Antikörper wurde für IHC, ELISA, Coat und StM validiert. Er ist geeignet, Elastin in Proben von Human zu detektieren.

Kurzübersicht für Elastin Antikörper (ABIN6939301)

Target: Elastin (ELN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Elastin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)

Klon: ELN-1981

Produktdetails anti-Elastin Antikörper

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human Elastin protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: A549 or U-2197 cells. Liver, Kidney, Lung or Intestine.

Known Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Elastin

Target: Elastin (ELN)

Andere Bezeichnung: ELN

Hintergrund: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Molekulargewicht: 70kDa

Gen-ID: 2006

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization