alpha Fetoprotein Antikörper

Produktnummer ABIN6939236

Dieser Maus Monoklonal Antikörper detektiert spezifisch alpha Fetoprotein in IHC. Es zeigt Reaktivität gegenüber Proben von Human, Schwein, Hund und Affe.

Kurzübersicht für alpha Fetoprotein Antikörper (ABIN6939236)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reaktivität: Human, Schwein, Hund, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser alpha Fetoprotein Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: C3

Produktdetails anti-alpha Fetoprotein Antikörper

Verwendungszweck: AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody

Spezifität: It recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha-fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Keine Kreuzreaktivität: Rind (Kuh), Maus, Ratte (Rattus)

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Alpha feto protein (AFP) Purified from serum of a hepatoma patient

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Hep-G2 cells. Fetal liver or hepatocellular carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Andere Bezeichnung: AFP

Hintergrund:

Alpha fetoglobulin, FETA, HPAFP

Hep-G2 cells. Fetal liver or hepatocellular carcinoma.

Molekulargewicht: 70kDa

Gen-ID: 174, 518808

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process