UCHL1 Antikörper
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- Target Alle UCHL1 Antikörper anzeigen
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser UCHL1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
- Kreuzreaktivität (Details)
- Human. Mouse. Rat. Cow. Pig. Dog.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Native UchL1 (PGP9.5) protein from brain
- Klon
- 31A3
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product UCHL1 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: T98G cells. Cerebellum.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- Andere Bezeichnung
- UCHL1 (UCHL1 Produkte)
- Synonyme
- PARK5 antikoerper, PGP 9.5 antikoerper, PGP9.5 antikoerper, PGP95 antikoerper, Uch-L1 antikoerper, UCH-L1 antikoerper, UCHL1 antikoerper, cb358 antikoerper, wu:fc55h08 antikoerper, park5 antikoerper, pgp9.5 antikoerper, uch-l1 antikoerper, MGC132191 antikoerper, uchl1 antikoerper, AW822034 antikoerper, C88048 antikoerper, R75593 antikoerper, UCHL-1 antikoerper, gad antikoerper, ubiquitin C-terminal hydrolase L1 antikoerper, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) antikoerper, ubiquitin C-terminal hydrolase L1 L homeolog antikoerper, ubiquitin carboxyl-terminal esterase L1 antikoerper, ubiquitin carboxy-terminal hydrolase L1 antikoerper, UCHL1 antikoerper, uchl1 antikoerper, uchl1.L antikoerper, LOC100304750 antikoerper, Uchl1 antikoerper
- Hintergrund
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Gracile Axonal Dystrophy, Neuron Cytoplasmic Protein 9.5, Park5, Parkinson Disease 5, PGP95, Protein Gene Product 9.5, Ubiquitin Carboxyl-terminal Esterase L1, Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1, Ubiquitin Thioesterase L1, Ubiquitin Thiolesterase L1,PGP9.5 / UchL1 (pan-Neuronal Marker)
Cellular localisation: Cytoplasmic. Endoplasmic Reticulum membrane - Molekulargewicht
- 20-30kDa
- Gen-ID
- 7345, 518731
- UniProt
- P09936
- Pathways
- Feeding Behaviour
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