TTR Antikörper

Produktnummer ABIN6938683

Der Maus Monoklonal anti-TTR Antikörper (Klon CPTC-TTR-1) (ABIN6938683) detektiert spezifisch TTR in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TTR Antikörper (ABIN6938683)

Target: TTR (Transthyretin (TTR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: CPTC-TTR-1

Produktdetails anti-TTR Antikörper

Verwendungszweck: Transthyretin (Prealbumin) Antibody

Spezifität: Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human full-length protein

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HepG2 cell lysate or human kidney or Liver tissue lysate (WB).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: TTR

Hintergrund:

Transthyretin, PALB, HsT2651, prealbumin, amyloidosis type 1, ATTR, TBPA, CTS, CTS1, carpal tunnel syndrome 1, thyroxine-binding prealbumin, prealbumin, HEL111, TTR protein, Epididymis luminal protein 111, prealbumin thyroxine binding, senile systemic amyloidosis antibody

HepG2 cell lysate or human kidney or Liver tissue lysate (WB).

Molekulargewicht: 15kDa

Gen-ID: 7276, 427202

UniProt: P02766

Pathways: Hormone Transport