Rekombinanter TIMP2 Antikörper (N-Term)
Kurzübersicht für Rekombinanter TIMP2 Antikörper (N-Term) (ABIN6938579)
Target
Alle TIMP2 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 56-66, N-Term
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Verwendungszweck
- Recombinant TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Antibody
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Spezifität
- It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
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Kreuzreaktivität (Details)
- Human. Mouse. Rat. Guinea Pig. Rabbit. Cow. Zebrafish.
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Aufreinigung
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)
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Isotyp
- IgG1, kappa
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Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Andere Bezeichnung
- TIMP2
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Hintergrund
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Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, TIMP2, Tissue Inhibitor of Metalloproteinase 2
Colon, Endometrial, HeLa cells. Normal Placenta. Breast, Prostate or Ovarian Carcinoma.
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Molekulargewicht
- 21kDa
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Gen-ID
- 7077, 633514
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UniProt
- P16035
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Pathways
- cAMP Metabolic Process
Target
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