Trefoil Factor 2 Antikörper (C-Term)

Produktnummer ABIN6938528

Produktdetails anti-Trefoil Factor 2 Antikörper

Target: Trefoil Factor 2 (TFF2)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Trefoil Factor 2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Coating (Coat)

Spezifität: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2.

Klon: GE16C

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order Ab without BSA & Azide),Optimal dilution for a specific application should be determined.

Positive_Control: Human stomach or duodenum tissues (IHC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Trefoil Factor 2

Target: Trefoil Factor 2 (TFF2)

Andere Bezeichnung: TFF2 (TFF2 Produkte)

Synonyme: TFF2 antikoerper, SML1 antikoerper, SP antikoerper, PSP antikoerper, p4 antikoerper, p4-a antikoerper, sml1 antikoerper, xP4 antikoerper, xp4.1 antikoerper, mSP antikoerper, trefoil factor 2 antikoerper, trefoil factor 2 S homeolog antikoerper, trefoil factor 2 (spasmolytic protein 1) antikoerper, TFF2 antikoerper, Tff2 antikoerper, tff2.S antikoerper

Hintergrund: SML1, SP, Spasmolysin, Spasmolytic polypeptide, TFF2, trefoil factor 2 (spasmolytic protein 1), Trefoil factor 2, Trefoil factor 2 precursor,Trefoil factor 2 / TFF2
Cellular localisation: Secreted.

Molekulargewicht: 14kDa

Gen-ID: 7032, 2979

UniProt: Q03403