Rekombinanter SOX9 Antikörper
Kurzübersicht für Rekombinanter SOX9 Antikörper (ABIN6938418)
Target
Alle SOX9 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) [MIM:114290]: Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant human full-length SOX9 protein
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Isotyp
- IgG
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Applikationshinweise
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Known_Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Human Skin Hair follicles.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))
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Andere Bezeichnung
- SOX9
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Hintergrund
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CMD 1, campomelic dysplasia autosomal sex reversal, SRA1, SRXX2, SRXY10, SRY (sex determining region Y) box 9, SRY related HMG box gene 9, Transcription factor SOX 9,SOX9 / SRY-box 9
Cellular localisation: Nuclear -
Molekulargewicht
- 56kDa
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Gen-ID
- 6662, 647409
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UniProt
- P48436
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Pathways
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Target
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