Rekombinanter SOX9 Antikörper

Produktnummer ABIN6938417

Dieser Maus Monoklonal Antikörper detektiert spezifisch SOX9 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter SOX9 Antikörper (ABIN6938417)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOX9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: RSOX9-2288

Produktdetails anti-SOX9 Antikörper

Verwendungszweck: Recombinant SOX9 / SRY-box 9 Antibody

Spezifität: The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) [MIM:114290]: Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

Immunogen: Recombinant human full-length SOX9 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunoprecipitation (2-4 μg/mg protein),Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human skin hair follicles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Andere Bezeichnung: SOX9

Hintergrund:

CMD 1, campomelic dysplasia autosomal sex reversal, SRA1, SRXX2, SRXY10, SRY (sex determining region Y) box 9, SRY related HMG box gene 9, Transcription factor SOX 9

Human skin hair follicles.

Molekulargewicht: 56kDa

Gen-ID: 6662, 647409

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development