s100a4 Antikörper (AA 1-200)
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- Target Alle s100a4 (S100A4) Antikörper anzeigen
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
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Bindungsspezifität
- AA 1-200
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser s100a4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, 64 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
- Kreuzreaktivität (Details)
- Human. Mouse.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa 1-200) of human S100A4 protein (exact sequence is proprietary)
- Klon
- S100A4-1481
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product S100A4 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: PANC-1, HeLa, A549 or A375 cells (IF/FACS). HeLa, A549, T98G or A375 cell lysate (WB). Human placenta tissue (IHC).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
- Andere Bezeichnung
- S100A4 (S100A4 Produkte)
- Synonyme
- 18A2 antikoerper, 42A antikoerper, CAPL antikoerper, FSP1 antikoerper, MTS1 antikoerper, P9KA antikoerper, PEL98 antikoerper, 42a antikoerper, Capl antikoerper, FSp1 antikoerper, Mts1 antikoerper, PeL98 antikoerper, metastasin antikoerper, pk9a antikoerper, S100A4 antikoerper, P9ka antikoerper, RNP9KA antikoerper, S100 calcium binding protein A4 antikoerper, S100 calcium-binding protein A4 antikoerper, S100A4 antikoerper, S100a4 antikoerper
- Hintergrund
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S100A4, S100 calcium-binding protein A4, Calvasculin, CAPL, Fibroblast specific protein 1 (FSP1), Leukemia multidrug resistance associated protein, Malignant transformation suppression 1 (MTS1), Metastasin, Placental calcium-binding protein,S100A4 / Metastasin / Calvasculin (Marker of Tumor Metastasis)
Cellular localisation: Cytoplasmic and nuclear - Molekulargewicht
- 10-12kDa
- Gen-ID
- 6275, 654444
- UniProt
- P26447
- Pathways
- S100 Proteine
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