RNLS Antikörper (AA 34-235)

Produktnummer ABIN6938322

Produktdetails anti-RNLS Antikörper

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Bindungsspezifität: AA 34-235

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RNLS Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Spezifität: Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human RNLS protein fragment (around aa 34-235) (exact sequence is proprietary)

Klon: RNLS-1940

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: 293T cells. Heart or Kidney.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu RNLS

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Andere Bezeichnung: RNLS (RNLS Produkte)

Synonyme: zgc:92286 antikoerper, C10orf59 antikoerper, RENALASE antikoerper, 6530404N21Rik antikoerper, AI452315 antikoerper, AW060440 antikoerper, RGD1309804 antikoerper, renalase, FAD dependent amine oxidase antikoerper, renalase, FAD-dependent amine oxidase antikoerper, RNLS antikoerper, rnls antikoerper, Rnls antikoerper

Hintergrund: Chromosome 10 open reading frame 59, MAO C, MAO-C, Monoamine oxidase-C, Renalase, Renalase FAD dependent amine oxidase, RNLS,Renalase (Renal Cell Marker)
Cellular localisation: Secreted

Molekulargewicht: 38kDa

Gen-ID: 55328, 149849

UniProt: Q5VYX0