ODC1 Antikörper

Produktnummer ABIN6938102

Produktdetails anti-ODC1 Antikörper

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ODC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Kreuzreaktivität (Details): Human. Mouse. Rat.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human ODC-1 protein

Klon: ODC1-485

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (0.5-1 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: PC3 or LNCaP cells. Placental tissue lysate. Placenta, Prostate or Testicular carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu ODC1

Target: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Andere Bezeichnung: ODC1 (ODC1 Produkte)

Synonyme: CG8721 antikoerper, Dmel\\CG8721 antikoerper, dodc1 antikoerper, odc antikoerper, fc54f04 antikoerper, fi06d08 antikoerper, CHUNP6922 antikoerper, wu:fc54f04 antikoerper, wu:fi06d08 antikoerper, odc2 antikoerper, xODC1 antikoerper, xodc2 antikoerper, DDBDRAFT_0204020 antikoerper, DDBDRAFT_0237755 antikoerper, DDB_0204020 antikoerper, DDB_0237755 antikoerper, ODC antikoerper, odc1 antikoerper, ODC1 antikoerper, Odc antikoerper, odc1-a antikoerper, Ornithine decarboxylase 1 antikoerper, ornithine decarboxylase 1 antikoerper, ornithine decarboxylase antikoerper, diaminopimelate decarboxylase antikoerper, Orn/DAP/Arg decarboxylase 2 domain-containing protein antikoerper, Diaminopimelate decarboxylase antikoerper, Ornithine decarboxylase antikoerper, ornithine decarboxylase 1 L homeolog antikoerper, ornithine decarboxylase, structural 1 antikoerper, Odc1 antikoerper, odc1 antikoerper, ODC1 antikoerper, odc antikoerper, RR_RS04895 antikoerper, ASA_RS06380 antikoerper, LOC100232922 antikoerper, odc1.L antikoerper, odc-1 antikoerper

Hintergrund: Ornithine decarboxylase structural 1, RNODC,Ornithine Decarboxylase-1 (ODC-1)
Cellular localisation: Cytoplasmic

Molekulargewicht: 53kDa

Gen-ID: 4953, 467701

UniProt: P11926