Rekombinanter NKX2-8 Antikörper (AA 10-123)

Produktnummer ABIN6938071

Dieses Anti-NKX2-8-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von NKX2-8 in ELISA, IHC und Coat. Geeignet für Human.

Kurzübersicht für Rekombinanter NKX2-8 Antikörper (AA 10-123) (ABIN6938071)

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NKX2-8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Coating (Coat)

Klon: NKX28-3233R

Produktdetails anti-NKX2-8 Antikörper

Bindungsspezifität: AA 10-123

Spezifität: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: PC3 or MCF-7 cells. Human Liver, Kidney or Thyroid tissue (IHC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Andere Bezeichnung: NKX2-8

Hintergrund: Homeobox protein NK-2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX2G, NKX2H, OTTHUMP00000027959,NKX2.8
Cellular localisation: Nucleus and cytoplasm.

Molekulargewicht: 26kDa

Gen-ID: 26257, 234763

UniProt: O15522