NKX2-8 Antikörper (AA 10-123)

Produktnummer ABIN6938070

Produktdetails anti-NKX2-8 Antikörper

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Bindungsspezifität: AA 10-123

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NKX2-8 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Coating (Coat), Flow Cytometry (FACS)

Spezifität: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)

Klon: NKX28-2548

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (2-4 μg/mL), ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Human Liver, Kidney or Thyroid tissue (IHC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Andere Bezeichnung: NKX2-8 (NKX2-8 Produkte)

Synonyme: NKX2.8 antikoerper, NKX2H antikoerper, Nkx2-9 antikoerper, Nkx-2.9 antikoerper, Nkx2-8 antikoerper, Nkx2.9 antikoerper, tinman antikoerper, NK2 homeobox 8 antikoerper, NK2 homeobox 9 antikoerper, NKX2-8 antikoerper, Nkx2-9 antikoerper, Nkx2-8 antikoerper

Hintergrund: Homeobox protein NK 2 homolog H, Homeobox protein NK-2 homolog H, Homeobox protein Nkx 2.8, Homeobox protein Nkx-2.8, NK 2 homolog 8, NK 2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX28_HUMAN, NKX2G, NKX2H, OTTHUMP00000027959,NKX2.8
Cellular localisation: Nuclear and Cytoplasm.

Molekulargewicht: 26kDa

Gen-ID: 26257, 234763

UniProt: O15522