NKX2-8 Antikörper (AA 10-123)

Produktnummer ABIN6938069

Dieser Maus Monoklonal Antikörper detektiert spezifisch NKX2-8 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für NKX2-8 Antikörper (AA 10-123) (ABIN6938069)

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NKX2-8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: NKX28-2547

Produktdetails anti-NKX2-8 Antikörper

Bindungsspezifität: AA 10-123

Verwendungszweck: NKX2.8 Antibody

Spezifität: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (0.5 μg-1 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: PC3 or MCF-7 cells. Human Liver, Kidney or Thyroid tissue (IHC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Andere Bezeichnung: NKX2-8

Hintergrund:

Homeobox protein NK 2 homolog H, Homeobox protein NK-2 homolog H, Homeobox protein Nkx 2.8, Homeobox protein Nkx-2.8, NK 2 homolog 8, NK 2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX28_HUMAN, NKX2G, NKX2H, OTTHUMP00000027959

Kidney or Thyroid tissue (IHC)., PC3 or MCF-7 cells. Human Liver

Molekulargewicht: 26kDa

Gen-ID: 26257, 234763

UniProt: O15522