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MUC1 Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MUC1 in IHC (f). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6937928

Kurzübersicht für MUC1 Antikörper (ABIN6937928)

Target

Alle MUC1 Antikörper anzeigen
MUC1 (Mucin 1 (MUC1))

Reaktivität

  • 365
  • 77
  • 38
  • 16
  • 6
  • 6
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 244
  • 146
  • 3
  • 1
  • 1
Maus

Klonalität

  • 216
  • 169
  • 9
Monoklonal

Konjugat

  • 198
  • 32
  • 19
  • 14
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 8
  • 7
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Dieser MUC1 Antikörper ist unkonjugiert

Applikation

  • 211
  • 201
  • 139
  • 105
  • 81
  • 78
  • 47
  • 47
  • 44
  • 23
  • 19
  • 16
  • 14
  • 13
  • 13
  • 6
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon

MUC1-520
  • Spezifität

    In Western blotting, it recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Human milk-fat globule membranes (HMFGM)

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    Known_Application: Immunohistology (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    MUC1 (Mucin 1 (MUC1))

    Andere Bezeichnung

    MUC1

    Hintergrund

    Breast carcinoma-associated antigen DF3, CA15-3, Carcinoma-associated mucin Episialin, Epithelial Membrane Antigen, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, Mucin 1 cell surface associated, Mucin-1 subunit beta, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epithelial membrane antigen, Tumor-associated mucin,MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)
    Cellular localisation: Cytoplasmic & Cell Surface

    Molekulargewicht

    265-400kDa

    Gen-ID

    4582, 89603

    UniProt

    P15941

    Pathways

    Negative Regulation of intrinsic apoptotic Signaling
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