MLANA Antikörper
Kurzübersicht für MLANA Antikörper (ABIN6937854)
Target
Alle MLANA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- MART-1 / Melan-A / MLANA (Melanoma Marker) Antibody
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Spezifität
- This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
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Keine Kreuzreaktivität
- Maus, Ratte (Rattus)
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Kreuzreaktivität (Details)
- Human. Horse. Does not react with Mouse or Rat.
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Aufreinigung
- 200ug/ml of Ab produced in CHO cell mammalian-based expression system.
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Immunogen
- Recombinant hMART-1 protein
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Isotyp
- IgG2b, lambda
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anti-Melan A (MLANA) antibody
MLANA Reaktivität: Human, Maus, Ratte WB, IHC, IF, FACS Wirt: Maus Monoclonal M2-9E3 unconjugated
anti-Melan A (MLANA) antibodyMLANA Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Monoclonal MLANA-1761R unconjugated Recombinant Antibody
anti-Melan A (MLANA) antibodyMLANA Reaktivität: Human, Pferd WB, IHC Wirt: Maus Monoclonal M2-7C10 unconjugated
anti-Melan A (MLANA) antibodyMLANA Reaktivität: Human, Maus, Ratte, Hund WB, IHC, IF, FACS Wirt: Maus Monoclonal A103 unconjugated
anti-Melan A (MLANA) antibodyMLANA Reaktivität: Human, Maus, Ratte, Hund WB, IHC Wirt: Kaninchen Monoclonal MLANA-1409R unconjugated Recombinant Antibody
anti-Melan A (MLANA) antibodyMLANA Reaktivität: Human, Maus, Ratte, Hund WB, IHC Wirt: Maus Monoclonal rMLANA-788 unconjugated Recombinant Antibody
anti-Melan A (MLANA) (AA 48-118) antibodyMLANA Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Melan A (MLANA) (AA 1-118) antibodyMLANA Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Melan A (MLANA) (full length) antibodyMLANA Reaktivität: Human IHC Wirt: Maus Monoclonal 901M- unconjugated Recombinant Antibody
anti-Melan A (MLANA) (AA 48-118) antibodyMLANA Reaktivität: Human ELISA Wirt: Maus Monoclonal 2F3B7 unconjugated
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Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: SK-MEL-13 and SK-MEL-19 melanoma cell lines. Human melanoma tissues.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- MLANA (Melan A (MLANA))
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Andere Bezeichnung
- MLANA
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Hintergrund
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Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA
SK-MEL-13 and SK-MEL-19 melanoma cell lines. Human melanoma tissues, Colo-38 cells
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Molekulargewicht
- 20-22kDa (doublet)
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Gen-ID
- 2315, 154069
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UniProt
- Q16655
Target
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