MAGEA4 Antikörper
Kurzübersicht für MAGEA4 Antikörper (ABIN6937797)
Target
Alle MAGEA4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human MAGEA4 protein
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Isotyp
- IgG2c kappa
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Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HepG2 cell lysate, melanoma, testes and placenta.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- MAGEA4 (Melanoma Antigen Family A, 4 (MAGEA4))
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Andere Bezeichnung
- MAGEA4
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Hintergrund
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CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, cancer/testis antigen 1.4, Melanoma-associated antigen 4,Melanoma Antigen Family A, 4 / MAGEA4
Cellular localisation: Cytoplasmic and nuclear. -
Molekulargewicht
- 45-50kDa
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Gen-ID
- 4103, 37107
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UniProt
- P43358
Target
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