LGALS1/Galectin 1 Antikörper (AA 12-108)
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- Target Alle LGALS1/Galectin 1 (LGALS1) Antikörper anzeigen
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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Bindungsspezifität
- AA 12-108
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LGALS1/Galectin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa12-108) of human Galectin-1 protein (exact sequence is proprietary)
- Klon
- GAL1-1831
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product LGALS1 Primärantikörper
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- Applikationshinweise
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Known_Application: Western Blot (1-2 μg/mL), ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: JEG-3, HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Andere Bezeichnung
- LGALS1 (LGALS1 Produkte)
- Synonyme
- GAL1 antikoerper, GBP antikoerper, Galectin-1 antikoerper, LGAS1 antikoerper, LGALS1 antikoerper, MGC64502 antikoerper, GB10026 antikoerper, AA410090 antikoerper, Gal-1 antikoerper, Galbp antikoerper, L-14.5 antikoerper, L14 antikoerper, Lect14 antikoerper, galectin-1 antikoerper, Galaptin antikoerper, galectin 1 antikoerper, galectin-1 antikoerper, lectin, galactoside-binding, soluble, 1 L homeolog antikoerper, protein enabled antikoerper, lectin, galactose binding, soluble 1 antikoerper, LGALS1 antikoerper, Lgals1 antikoerper, CC1G_05003 antikoerper, CC1G_05004 antikoerper, lgals1.L antikoerper, LOC408848 antikoerper
- Hintergrund
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14 kDa laminin-binding protein, Beta-galactoside-binding lectin L-14-I, Gal-1, GAL1, Galaptin, Galectin-1, HLBP14, HPL, Lactose-binding lectin 1, Lect14, Lectin galactoside-binding soluble 1, LGALS1, MAPK activating protein MP12, S-Lac lectin 1,Galectin-1 / Human Placental Lactogen (hPL)
Cellular localisation: Secreted (extracellular matrix) - Molekulargewicht
- 14kDa
- Gen-ID
- 3956, 445351
- UniProt
- P09382
- Pathways
- Carbohydrate Homeostasis
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