L1CAM Antikörper
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- Target Alle L1CAM Antikörper anzeigen
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser L1CAM Antikörper ist unkonjugiert
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Applikation
- ELISA, Coating (Coat)
- Spezifität
- Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Homogenous suspension of 16-week human fetal brain
- Klon
- UJ127
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product L1CAM Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Neuroblastomas or Schwannomas.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- L1CAM (L1 Cell Adhesion Molecule (L1CAM))
- Andere Bezeichnung
- L1CAM (L1CAM Produkte)
- Synonyme
- l1cam-a antikoerper, CAML1 antikoerper, CD171 antikoerper, HSAS antikoerper, HSAS1 antikoerper, MASA antikoerper, MIC5 antikoerper, N-CAM-L1 antikoerper, N-CAML1 antikoerper, NCAM-L1 antikoerper, S10 antikoerper, SPG1 antikoerper, L1 antikoerper, Hsas antikoerper, Hyd antikoerper, NCAML1 antikoerper, L1 cell adhesion molecule S homeolog antikoerper, L1 cell adhesion molecule antikoerper, l1cam.S antikoerper, L1CAM antikoerper, L1cam antikoerper
- Hintergrund
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CAML1, HSAS1, Hyd, L1 Cell Adhesion Molecule, L1-NCAM, MASA, MIC5, NCAM-L1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, S10, SPG1,CD171 / NCAM-L1 (Axonal Marker)
Cellular localisation: Cell Surface - Molekulargewicht
- 220-240kDa
- Gen-ID
- 3897, 52818
- UniProt
- P32004
- Pathways
- Synaptic Membrane
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