KRT4 Antikörper (AA 181-292)
Kurzübersicht für KRT4 Antikörper (AA 181-292) (ABIN6937710)
Target
Alle KRT4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 181-292
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Verwendungszweck
- Cytokeratin 4 (KRT4) Antibody
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Spezifität
- Cytokeratin 4 (KRT4) is an intermediate filament protein associated with Cytokeratin 13 (KRT13). It is expressed in suprabasal cells of non-keratinized stratified squamous epithelium of esophagus, cornea, anus, larynx, pharynx and tongue. Decreased expression of KRT4 is associated with head and neck squamous carcinoma. It is helpful in differentiation of squamous cell carcinoma of esophagus origin from that of thyroid origin.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa 181-292) of human KRT4 protein (exact sequence is proprietary)
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Isotyp
- IgG1, kappa
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Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, A549 or A431 cells. Skin, Cervix or Esophagus.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- KRT4 (Keratin 4 (KRT4))
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Andere Bezeichnung
- KRT4
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Hintergrund
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CK4, CYK4, Cytokeratin 4, Keratin 4, Keratin type II cytoskeletal 4, KRT4
A549 or A431 cells. Skin, Cervix or Esophagus., HeLa
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Molekulargewicht
- ~67kDa
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Gen-ID
- 3851, 654610, 706527
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UniProt
- P19013
Target
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