Rekombinanter KRT16 Antikörper (C-Term)

Produktnummer ABIN6937671

Produktdetails anti-KRT16 Antikörper

Target: KRT16 (Keratin 16 (KRT16))

Antikörpertyp: Recombinant Antibody

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KRT16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment from the C-terminal of human Cytokeratin 16

Klon: KRT16-2043R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Tonsil, Skin. Bladder or Cervix.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu KRT16

Target: KRT16 (Keratin 16 (KRT16))

Andere Bezeichnung: KRT16 (KRT16 Produkte)

Synonyme: CK16 antikoerper, FNEPPK antikoerper, K16 antikoerper, K1CP antikoerper, KRT16A antikoerper, NEPPK antikoerper, AI324768 antikoerper, Krt1-16 antikoerper, Ka16 antikoerper, KRT16 antikoerper, Krt16 antikoerper, keratin 16 antikoerper, keratin 16, type I S homeolog antikoerper, keratin, type I cytoskeletal 16 antikoerper, KRT16 antikoerper, Krt16 antikoerper, krt16.S antikoerper, LOC101108147 antikoerper, LOC100714013 antikoerper

Hintergrund: CK16, Cytokeratin-16, Focal non epidermolytic palmoplantar keratoderma (FNEPPK / NEPPK), K1CP, Keratin Type I Cytoskeletal 16, Keratin-16, KRT16A,Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker)
Cellular localisation: Cytoplasmic

Molekulargewicht: 48kDa

Gen-ID: 3868, 655160

UniProt: P08779