Rekombinanter KRT16 Antikörper (C-Term)

Produktnummer ABIN6937670

Dieser Maus Monoklonal Antikörper detektiert spezifisch KRT16 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter KRT16 Antikörper (C-Term) (ABIN6937670)

Target: KRT16 (Keratin 16 (KRT16))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: RKRT16-1714

Produktdetails anti-KRT16 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Recombinant Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker) Antibody

Spezifität: Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment from the C-terminal of human Cytokeratin 16

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Tonsil, Skin. Bladder or Cervix.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu KRT16

Target: KRT16 (Keratin 16 (KRT16))

Andere Bezeichnung: KRT16

Hintergrund:

CK16, Cytokeratin-16, Focal non epidermolytic palmoplantar keratoderma (FNEPPK / NEPPK), K1CP, Keratin Type I Cytoskeletal 16, Keratin-16, KRT16A

HeLa cells. Tonsil, Skin. Bladder or Cervix.

Molekulargewicht: 48kDa

Gen-ID: 3868, 655160

UniProt: P08779