KRT15 Antikörper (C-Term)

Produktnummer ABIN6937659

Der Maus Monoklonal Anti-KRT15-Antikörper wurde für IHC (f) validiert. Er ist geeignet, KRT15 in Proben von Human zu detektieren.

Kurzübersicht für KRT15 Antikörper (C-Term) (ABIN6937659)

Target: KRT15 (Keratin 15 (KRT15))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT15 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon: LHK15

Produktdetails anti-KRT15 Antikörper

Bindungsspezifität: C-Term

Spezifität: Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

Kreuzreaktivität (Details): Human. Rat. Cow.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: A 17 amino acids synthetic peptide from the C- terminal of Human Cytokeratin 15

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: A431 cells. Skin or Colon.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu KRT15

Target: KRT15 (Keratin 15 (KRT15))

Andere Bezeichnung: KRT15

Hintergrund: CK15, Cytokeratin 15, K1CO, Ka15, Keratin 15 basic, Keratin 15 beta, Keratin complex 1 acidic gene 15, Keratin type I cytoskeletal 15, KRT15, KRTB, KRTL15, Type I cytoskeletal 15, Type I keratin Ka15,Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker)
Cellular localisation: Cytoplasmic

Molekulargewicht: 52kDa

Gen-ID: 3866, 654570

UniProt: P19012