KRT14 Antikörper (C-Term)
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- Target Alle KRT14 Antikörper anzeigen
- KRT14 (Keratin 14 (KRT14))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser KRT14 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.
- Kreuzreaktivität (Details)
- Human. Mouse. Rat.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14.
- Klon
- LL002
- Isotyp
- IgG3 kappa
- Top Product
- Discover our top product KRT14 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, A549 or A431 cells. Skin or Squamous cell carcinoma.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- KRT14 (Keratin 14 (KRT14))
- Andere Bezeichnung
- KRT14 (KRT14 Produkte)
- Synonyme
- CK14 antikoerper, EBS3 antikoerper, EBS4 antikoerper, K14 antikoerper, NFJ antikoerper, AI626930 antikoerper, Krt-1.14 antikoerper, Krt1-14 antikoerper, Ka14 antikoerper, ouro2 antikoerper, keratin 14 antikoerper, keratin 14, type I L homeolog antikoerper, KRT14 antikoerper, Krt14 antikoerper, krt14.L antikoerper
- Hintergrund
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CK-14, Dowling Meara, ebs3, ebs4, Epidermolysis Bullosa Simplex, k14, Keratin 14, Keratin Type I Cytoskeletal 14, Koebner, krt14, NFJ,Cytokeratin 14 (KRT14) (Squamous Cell Marker)
Cellular localisation: Cytoplasmic - Molekulargewicht
- 50kDa
- Gen-ID
- 3861, 6545380
- UniProt
- P02533
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